Enantiomer separation is used for chiral substances which – like our hands (greek: “ch[e]ir”) – are non-superimposable mirror images of each other.
Chromatography with chiral stationary phases allows separation of these enantiomers, which otherwise show identical physical and chemical properties. While chiral HPLC is mainly used for the separation of pharmaceutically active ingredients, chiral GC is the method of choice for the analysis of fragrances, flavors and other volatile substances.
There is a Machery-Nagel paper explaing the different phases for chiral gas chromatography based on modified cyclodextrins and their application for enantiomer separation of certain groups of substances
View the full article on our website.
Save to del.icio.us
0 comments:
Post a Comment